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Multiple methylation modified peptides
Kang Long independent research and development of biological science and technology:Fmoc-Lys(Me,Boc)-OH, Fmoc-Lys(Me)2-OH , Fmoc-Lys(Me)3-OH,Fmoc- Arg (Me)2-OH symmetric and Fmoc- Arg (Me)2-OH asymmetric And successfully methylated peptide synthesis.
We have done the methylation of polypeptide instances:
| No. | Peptide Sequence |
| 1 | TGR(me1)ARARARGRARGQE-K(Biotin) {Arg(Me)}@-Lys(Biotin) |
| 2 | TGR(me2a)ARARARGRARGQE-K(Biotin) {{Arg(Me)2} asymmetrical}@-Lys(Biotin) |
| 3 | TGR(me2s)ARARAR(me2s)GRAR(me2s)GQE-K(Biotin) {{Arg(Me)2} asymmetrical}@{{Arg(Me)2} symmetr ical}@{{Arg(Me)2} symmetrical}@-Lys(Biotin) |
| 4 | biotin-minipeg-Leu-Gly-Lys-Gly-Gly-Ala-Lys-Arg-His-Arg-Lys(me2)-Val-Leu-Arg-Asp-Asn-Ile-Gln-Gly- Ile-Thr Biotin-@{Mini-PEG}@{Lys(Me2)} |
