A beta protein (beta amyoid peptide) is 1984 Glenne found neuritis plaques in the brain, such as main ingredients, it is A composed of 39 ~ 43 of amino acids, with beta folding conformation of proteins, so called beta amyloid protein.
Beta Amyloid peptide 1-42 (Amyloid beta 1 to 42, hereinafter referred to as A beta 42) is the main component of senile plaques have nerve toxicity, it is Alzheimer's disease (Alzheimer 'sDisease, AD) of the main causes.
A beta 1 to 42 C the 10 amino acid residues 33-42 and 17-21 five amino acid residues with high hydrophobicity, constituted A beta 1-42 scanty water; 28-42 amino acid residues formed beta folding conformation probability, and 9-21 amino acid residues may also form A beta folding conformation, and beta folding conformation is conducive to A beta 1-42 deposit and plaques.
As A beta 1-42 protein in alzheimer disease (AD) and to play an important role in the immune therapy, thus further clarify A beta 1 to 42 protein in AD pathogenesis in detail and its role in the immune therapy is of great significance to solve the AD.
Kang Long for you to supply a series of beta amyoid peptides, common types are equipped with inventory, quality assurance!
We have done instances:
NO. | Peptide Name | Peptide Sequence |
1 | β-Amyloid (1-42), Human | Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe -Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala |
2 | β-Amyloid (1-42), Rat | H-Asp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Phe-Glu-Val-Arg-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH |
3 | β-Amyloid (1-40), Rat | H-Asp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Phe-Glu-Val-Arg-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH |
4 | β-Amyloid (1-40) | H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH |